Plazmada Wil- lebrand etmeninin ve antihemofilik A etmeninin (etmen VIII) azlığına bağlı yapısal hastalık. Kanama süresinin uzaması, cam bilya üzerinde trombositlerin birleşiminde azalma ve ristosetin adlı antibiyotiğin varlığında bu birleşmenin yok olmasıyla belirgindir.
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